I looked for specific studies backing that up but this far do not see that result published anywhere.
There are studies but I’m not yet finding results except the following excerpt from feb 10th, which is not endorsing it as treatment.
New England journal of medicine.
Effectiveness of Hydroxychloroquine in Covid-19 Patients (Covid)
https://www.nejm.org/doi/full/10.1056/NEJMc2035374
“In vitro studies show that the effect of hydroxychloroquine is mainly mediated by alkalinization of the phagolysosomes,4 where it can concentrate about 1500 times more than in plasma. This effect can be obtained with low doses of hydroxychloroquine because of its long elimination half-life. High doses may therefore be useless or even deleterious because of the anti-interferon action of hydroxychloroquine,5 which may result in a more severe form of Covid-19.6 The dose used in the RECOVERY trial, the second highest after that in the trial conducted by Borba et al., arouses concern because it may have been a disease-aggravating factor negating the therapeutic effect.”
From the same study
https://www.nejm.org/doi/full/10.1056/NE...om_article
“ The enrollment of patients in the hydroxychloroquine group was closed on June 5, 2020, after an interim analysis determined that there was a lack of efficacy. Death within 28 days occurred in 421 patients (27.0%) in the hydroxychloroquine group and in 790 (25.0%) in the usual-care group (rate ratio, 1.09; 95% confidence interval [CI], 0.97 to 1.23; P=0.15). Consistent results were seen in all prespecified subgroups of patients. The results suggest that patients in the hydroxychloroquine group were less likely to be discharged from the hospital alive within 28 days than those in the usual-care group (59.6% vs. 62.9%; rate ratio, 0.90; 95% CI, 0.83 to 0.98). ”
There is a comment rebuttal but a comment isn’t a study.
Over time we will have results to say definitively but again this isn’t a silver bullet, though I heard of something out of Vancouver if I’m recalling correctly, not sure yet as details hadn’t been released just yet to avoid disinformation like has happened with other potential treatments.
Ah details were released but it isn’t approved for treatment as there isn’t enough safety data as of January.
I just wanna see people’s lovely faces again, hug people, share meals willy nilly, go back to the volunteer opportunities at the retirement home.
Eventually this too shall pass.
There are studies but I’m not yet finding results except the following excerpt from feb 10th, which is not endorsing it as treatment.
New England journal of medicine.
Effectiveness of Hydroxychloroquine in Covid-19 Patients (Covid)
https://www.nejm.org/doi/full/10.1056/NEJMc2035374
“In vitro studies show that the effect of hydroxychloroquine is mainly mediated by alkalinization of the phagolysosomes,4 where it can concentrate about 1500 times more than in plasma. This effect can be obtained with low doses of hydroxychloroquine because of its long elimination half-life. High doses may therefore be useless or even deleterious because of the anti-interferon action of hydroxychloroquine,5 which may result in a more severe form of Covid-19.6 The dose used in the RECOVERY trial, the second highest after that in the trial conducted by Borba et al., arouses concern because it may have been a disease-aggravating factor negating the therapeutic effect.”
From the same study
https://www.nejm.org/doi/full/10.1056/NE...om_article
“ The enrollment of patients in the hydroxychloroquine group was closed on June 5, 2020, after an interim analysis determined that there was a lack of efficacy. Death within 28 days occurred in 421 patients (27.0%) in the hydroxychloroquine group and in 790 (25.0%) in the usual-care group (rate ratio, 1.09; 95% confidence interval [CI], 0.97 to 1.23; P=0.15). Consistent results were seen in all prespecified subgroups of patients. The results suggest that patients in the hydroxychloroquine group were less likely to be discharged from the hospital alive within 28 days than those in the usual-care group (59.6% vs. 62.9%; rate ratio, 0.90; 95% CI, 0.83 to 0.98). ”
There is a comment rebuttal but a comment isn’t a study.
Over time we will have results to say definitively but again this isn’t a silver bullet, though I heard of something out of Vancouver if I’m recalling correctly, not sure yet as details hadn’t been released just yet to avoid disinformation like has happened with other potential treatments.
Ah details were released but it isn’t approved for treatment as there isn’t enough safety data as of January.
I just wanna see people’s lovely faces again, hug people, share meals willy nilly, go back to the volunteer opportunities at the retirement home.
Eventually this too shall pass.
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