08-08-2021, 05:43 AM
(This post was last modified: 08-08-2021, 05:48 AM by LeiwoUnion.)
(08-07-2021, 08:16 PM)unity100 Wrote: If you are afraid of vaccines, get anything other than Pfizer/Biontech and Moderna. Only those two are mRNA vaccines. All the other vaccines, including Sinovac, are traditional vaccines.
This is only partially true. While these other vaccines (with the exception of sinovac) are not mRNA vaccines like the Pfitzer/Moderna they are not quite traditional vaccines either. They employ viral vectors as their 'active ingredient' instead of deactivated viruses. This active ingredient means that the adenoviral vector (which contains the nucleic acid sequence for coding the covid-19 spike protein) is brought into the host cell cytoplasm where the production of the immunization agent can commence, similar to mRNA vaccines. The main difference is the delivery agent itself where for the mRNA vaccines the delivery of the genetic code happens via a synthetic lipid nanoparticle while in the virus vector vaccines the delivery happens via a seminatural adenovirus shell. When the host cell has been breached via either lipid endocytosis or modified adenoviral infection the rest is pretty much identical. Modified covid-19 spike protein production. Sinovac on the other hand is true traditional vaccine which relies on the delivery of deactivated covid-19 viruses to produce immunization. There might be some other traditional type vaccines but I didn't go search for more info.