09-07-2012, 11:12 AM
(09-07-2012, 10:53 AM)Goldenratio Wrote: The brain is predominantly made up of cholesterol.
Statins drugs attack cholesterol formations.
As I understand it, some research has been done into it, but I haven't personally read the papers, so I don't want to post recalled hearsay.
Cholesterol, along with essential fatty acids such as DHA, are involved in the manufacture of the myelin sheath, which is essentially the insulation around our nerves. Without that, we cannot properly propagate electrical signals down them.
Cholesterol is also found in all cell membranes where it acts as a kind of lubricant, allowing for protein channels to slide past one another.
Statin drugs inhibit the internal production of cholesterol by blocking an enzyme called HMG-CoA reductase, which controls the rate-limiting step of cholesterol manufacture. Incidentally, this enzyme is also critical in the production of CoQ10- which is essential for energy transfer in the mitochondria. This is the reason for many of the side effects.