Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD

Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD - Printable Version

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Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD - Cirocco - 04-19-2017

and psilocybin

Abstract

What is the level of consciousness of the psychedelic state? Empirically, measures of neural signal diversity such as entropy and Lempel-Ziv (LZ) complexity score higher for wakeful rest than for states with lower conscious level like propofol-induced anesthesia. Here we compute these measures for spontaneous magnetoencephalographic (MEG) signals from humans during altered states of consciousness induced by three psychedelic substances: psilocybin, ketamine and LSD. For all three, we find reliably higher spontaneous signal diversity, even when controlling for spectral changes. This increase is most pronounced for the single-channel LZ complexity measure, and hence for temporal, as opposed to spatial, signal diversity. We also uncover selective correlations between changes in signal diversity and phenomenological reports of the intensity of psychedelic experience. This is the first time that these measures have been applied to the psychedelic state and, crucially, that they have yielded values exceeding those of normal waking consciousness. These findings suggest that the sustained occurrence of psychedelic phenomenology constitutes an elevated level of consciousness - as measured by neural signal diversity.

https://www.nature.com/articles/srep46421

RE: Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD - Dekalb_Blues - 05-15-2017

~
[Image: you-must-be-at-least-this-high-to-ride.jpg]

[Image: you-must-be-at-least-this-high-to-ride.jpg]

RE: Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD - Coordinate_Apotheosis - 05-15-2017

To ride what, the Rabbit Hole of Life??

RE: Rationalists in Labs Fooling Around w/ Vitamin K & Acid, or, I Brake For Zebras - Dekalb_Blues - 05-15-2017

(05-15-2017, 06:12 AM)Coordinate_Apotheosis Wrote: To ride what, the Rabbit Hole of Life??

True that, too. (Disambiguated from the noted Vietnamese mystic, Truh That Thieu) But also:

[Image: u7Z2i.gif]

[Image: mr-bean-falling-asleep-roller-coaster-sn...06342Y.gif]

[Image: tumblr_mzxih6G1ZU1shf8zxo1_400.gif]

https://en.wikipedia.org/wiki/Ralph_Abraham_(mathematician)
https://infogalactic.com/info/Ralph_Abraham
http://www.maps.org/news-letters/v18n1/v18n1-MAPS_8-10.pdf
http://www.ralph-abraham.org/talks/transcripts/hyperspace.pdf

http://michaelwinkelman.com/about/
http://journals.sagepub.com/doi/abs/10.1177/153321010100600304
https://www.maps.org/news-letters/v17n3/v17n3_20-24.pdf
https://www.scribd.com/document/210722563/Shamanism-as-Original-Neurotheology

Moar random freebies useful for wasting your beautiful mind upon:
http://www.organiclab.narod.ru/books/DMT-The-spirit-molecule.pdf
http://en.booksee.org/g/Michael%20Winkelman
http://en.booksee.org/g/%20Ralph%20Abraham
http://en.booksee.org/s/?q=psychedelic+information+theory&e=1&t=0
http://en.booksee.org/g/Stanislav%20Grof
http://en.booksee.org/s/?q=john+c.+lilly&e=1&t=0

"Because the use of psychedelics creates higher states of consciousness it is the experience itself that may become addictive, not the drug or method." -- Some Wiseguy (probably high or jonesing while he said this, so disregard)

Some pertinent remarks from The Great Beyond: http://www.lawofone.info/results.php?q=lsd&o=s